Speak! was the first Eightfold series. Running for nine issues from April-July 2005, it chronicles the misadventures and moral dilemmas faced by its primary protagonist, Gregory Dingham, a young man who finds himself able to alter the course of reality itself by merely speaking his desires, and his associate, Harry Cash, an ex-convict/supervillain.
Most of the series is written in an accusative second-person, castigating Dingham for his behaviour. Author Tom Russell had stated that he intended it to be an exploration of the capacity for evil in human beings.